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Nobiletin
Category Monomer
Effectiveness Antisepsis and anti-inflammation / Antivirus / Anti-Cancer
Plant of origin Citrus nobilis Lour., C.aurantium L., C.reticulata Blanco
Molecular Formula C21H22O8
Molecular Mass 402.395
CAS No. 478-01-3
Function
Nobiletin seems to be a very noble phytochemical with many potential health benefits. The most studied properties of nobiletin are its anti-inflammatory and anti-cancer activities. Nobiletin also helps to lower cholesterol levels and some studies indicate that it may improve impaired memory loss and treat acne.
Anti-inflammatoryNumerous in-vivo and in-vitro studies have demonstrated the anti-inflammatory activity of nobiletin and its metabolites. Nobiletin acts directly as an antioxidant but also interferes with biological inflammatory processes. It inhibits the expression of genes involved in inflammation by blocking the binding of NF-kappaB with DNA. One study showed that nobiletin reduced airway inflammation of asthmatic rats. Treatment of skin cells with nobiletin also reduced inflammation caused by ultraviolet-B radiation.
Anti-cancerThe anti-cancer properties of nobiletin are supported by many scientific studies. Nobiletin act by its antiproliferation effect without being toxic to normal cells. Favourable results have been obtained on cancer cell lines of the liver, stomach, prostate and colon.
Cholesterol loweringA study with cultured macrophages demonstrated the cholesterol lowering and atherosclerosis inhibiting properties of nobiletin. Nobiletin also inhibits the formation of macrophage foam cells, macrophages loaded wit lipids, which build up on artery walls.
Memory lossOne study on a mice model showed that nobiletin my help to improve memory loss. The brains of the mice were chirurgically altered to obtain models of Alzheimer disease. It is not known if nobiletin improves the condition of human Alzheimer patients.
Acne treatmentWe found one study showing that nobiletin inhibited sebum production on hamsters and inhibited the proliferation of sebocytes, the cells that form the sebaceous gland. This observation led the researchers to conclude that nobiletin could be used as a drug for acne treatment.
Storage: 1 .Stored in cool & dry place
2 .Kept away from strong light and heat
Shelf Life: 2 years when properly stored
* Delivery Time.
We need 1-2 days to process your order before shipping.There are two shipping methoed. Fast Delivery: The delivery time for US, European countries the delivery will take 3-5 days.Slow Delivery: The delivery time for US, European countries the delivery will take 10-15 days.
* Tracking information.
After we ship package, customer receive automatic email with tracking details.
* Lost Package Policy.
If a package did not arrive in 4 weeks after the shipping date, then this package is treated as Lost. In this case a new package will be shipped to the customer provided we are able to give the same items as those purchased by the customer. If we are not able to provide the same items to substitute the lost ones we will either propose to the customer similar items or refund their cost as it will be mutually agree with the customer. If one or more items neither the same nor similar are available to be shipped, the customer can request to cancel the order entirely, thus the total cost of the order including shipping and handling cost will be fully refunded.
